To measure cross-linking amino acids in a collagen hydrolyzate using a conventional amino acid analyzer with ninhydrin detection, the bulk amino acids must be largely removed to avoid plugging the reaction coil. Tissue is thoroughly reacted with sodium borohydride to convert all intermediate cross-linking residues to their reduced, acid-stable forms. More vigorous reduction conditions may be used than when preparing profiles of tritium-labeled cross-links using NaB3H4<span> and direct amino acid analysis. </span>
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Individuals with glucose-6-phosphate dehydrogenase deficiency have increased resistance to malaria because the parasite does not survive well in cells with oxidative stress.
<h3>What is the link between G6P deficiency and malaria?</h3>
- Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked recessive disorder.
- G6PD protects cells from oxidative damage especially the RBCs whose main function is to carry oxygen.
- Mutation in the gene results in G6PD deficiency leading to oxidative stress which can lead to anemia (iron deficiency) as there is breakdown of RBCs.
- However, G6PD deficiency is quite common in parts of Africa, Middle East, and South Asia, which are the regions of high malaria endemism.
- This is due to natural selection in which G6PD deficiency is not eliminated from the population as it can protect people from malaria infection.
- Malaria parasite <em>Plasmodium</em> species does not survive well in cells with oxidative stress.
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Answer: they can be either dominant or recessive
Explanation: due to the effects of one Gene are usually inherited in a simple mendelian pattern.
The biological basis for assigning all human beings into a singe species is that there so many, even tons of living organisms living on earth. These organisms differ in their external and internal organs and so to differentiate them from them, they are being classified into kingdoms then classes then phylums then family.
