Answer:
Megaloblastic anemia is most often due to hypovitaminosis, specifically vitamin B12 (cobalamin) and folate deficiencies, which are necessary for the synthesis of DNA. [3] Copper deficiency and adverse drug reactions (due to drug interference with DNA synthesis) are other well-known causes of megaloblastic anemia.
Explanation:
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Natural selection involve natural causes while artificial selection is by human breeding or human intervention.
The process of domestication is called artificial selection. Like natural selection, artificial selection acts by allowing differential reproductive success to individuals with different genetically determined traits in order to increase the frequency of desirable traits in the population. Natural selection and selective breeding can both cause changes in animals and plants. The difference between the two is that natural selection happens naturally, but selective breeding only occurs when humans intervene.