Yes, it is true that Mammalian target of rapamycin pathway mutations cause hemimegalencephaly and focal cortical dysplasia.
Focal malformations of cortical development, including focal cortical dysplasia (FCD) and hemimegalencephaly (HME), are important causes of intractable childhood epilepsy.
Using targeted and exome sequencing on DNA from resected brain samples and non-brain samples from 53 patients with FCD or HME, we identified pathogenic germline and mosaic mutations in multiple PI3K/AKT pathway genes in 9 patients, and a likely pathogenic variant in 1 additional patient.
Our data confirm the association of DEPDC5 with sporadic FCD but also implicate this gene for the first time in HME. Our findings suggest that modulation of the mammalian target of rapamycin pathway may hold promise for malformation-associated epilepsy.
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By telling them if they children
The correct statement is liver cells possess transcriptional activators that are different from those of lens cells.
<h3>What are Transcriptional activators?</h3>
Transcriptional activators are specific protein sequences capable of activating gene expression.
These transcription factors (transcriptional activators) act to regulate gene expression in target cells.
Transcriptional activators are factors that enable the expression of certain genes in particular cell types.
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Answer:
Oxidative Phosphorylation
The mitochondria is one of the double membrane organelles with specialized energy-producing functions, that is, reduced nucleotides to finally form the cellular energy currency that is ATP. The 5'-triphosphate adenosine molecule (ATP) is synthesized in the inner mitochondrial membrane as a subsequent step to the electron transport chain through oxidative phosphorylation. This process takes advantage of the flow of protons or proton motive force, detected by an electrochemical differential of H +, to produce ATP through the complex V of the mitochondrial inner membrane. Together with photosynthesis, it is one of the most important energy transduction processes in the biosphere.
Oxidative phosphorylation: Synthesis of ATP
The mitochondria, in its inner membrane, is the place of the electron transport chain and oxidative phosphorylation, | Mitochondrial electronic transport and oxidative phosphorylation are the mechanisms that aerobic organisms use to synthesize ATP from reduced organic molecules.
Answer:
I have been around it my whole life people just get addicted. Its like this game that you realy love so you play it over and over again.
Explanation:
