Question

Two genes display an epistatic-hypostatic relationship. As discussed in lecture, if the two genes are part of a single genetic pathway such relationships are often informative about the order in which the corresponding genes act on that pathway. True or False, the epistatic gene typically acts downstream of the hypostatic static gene.

Answer 1

Although it is necessary to have an epistatic factor in order to hide the expression of a hypostatic gene, epistatic interactions can be both downstream and upstream (which correspond to negative and positive regulatory pathways, respectively)