Interesting question. The black death was a rather ready virus or as they called it a "plague". The reason it was so deadly it because it was a brand new virus/plague that the Europeans had never encounterd therefore being rather deadly for there immune system was not ready for it and had no way of treating it because it was an known virus from overseas. If you didn't know it was carried over on a ship where the virus was attached to a rat with further infected the crew and soon after the entire towb
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Policy innovators basically mean to come up with new policy or reforms for the benefit of the people. In the US Federalist system, states are allowed to come up with their own policies and share them with other states and the federal government. This allows them to be policy innovators.
The principle in Brown vs Board of Education was that "separate but equal" facilities violated the 14th Amendment. The "separate but equal" facilities that African Americans were put into was not really equal and therefore broke the 14th amendment.