It makes sense; but there are two phrases there that could be divided to make the sentence flow better.
“I am not happy with myself, nor will I ever be.”
<span>Their structure, can separate groups of people. This makes it difficult for people, goods, and ideas to move from one place to another. This would also affect the climate.</span>
<em>My Opinion:</em>
<em></em>
<em>(E) relating it to the words mesmerized audiences</em>
<em>Not sure tho, Good Luck! =)</em>