Answer:
Explanation:
The switch from glutamic acid to valine in position 6 of hemoglobin (HB) forms the basis of sickle cell anemia disease pathology.
Valine is hydrophobic and it's chain is shorter than glutamic acid. The lack of the carboxylic acid and shortness of valine will result in loss of the ionic interactions formed between the glutamic acid's carboxylic group and other amino acids. A hydrophobic cavity will form in the beta sheet of HB due to the short and hydrophobic structure of valine. For these reasons, the HB molecule will be less stable and insoluble in water. The insolubility is thought to be caused by fibril formation between the valine interacting with hydrophobic pocket residues of the adjacent HB molecule. This would in turn affect binding of oxygen to HB.
Answer:
A nucleotide is the basic building block of nucleic acids. RNA and DNA are polymers made of long chains of nucleotides. A nucleotide consists of a sugar molecule (either ribose in RNA or deoxyribose in DNA) attached to a phosphate group and a nitrogen-containing base.
Explanation:
Answer:
science is different from many other ways of learning because of the way it is done. Science relies on testing ideas with evidence gathered from the natural world.
Hope this helps
Answer:
carbon dioxide and water
Explanation:
carbon dioxide and water are the raw materials needed to start the reaction. They are on the left side of the equation so that is how you know.
Answer:
Kidneys
Explanation:
The kidneys remove wastes and excess water in the body through the urine, as urine flows from the kidneys to the bladder through two thin tubes located on both sides of the bladder called the ureter, and the bladder stores urine, and each of the kidneys consists of about one million filtering units called the renal tubular unit contains Each renal tubular unit has a filter called the glomerulus and tubule, and the renal tubular unit operates through a two-step process:
glomerulus: filters blood.
Tubule: Returns the necessary substances to the blood and removes waste.
