Answer:
Please list the statements there are to choose from, this way, even people outside your school and/or grade level will be able to answer your question.
Explanation:
Answer:
rRNA is located in the cytoplasm of a cell, where ribosomes are found. rRNA directs the translation of mRNA into proteins.
Answer:
Cytokinesis is the physical process of cell division, which divides the cytoplasm of a parental cell into two daughter cells. ... The contractile ring shrinks at the equator of the cell, pinching the plasma membrane inward, and forming what is called a cleavage furrow.
Explanation:
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Answer/Explanation:
(1) a mutation in the coding region, resulting in an inactive protein
To check to see if there is a mutation, you could extract the DNA from the cancer cells and then perform PCR to amplify the gene of interest. You could then perform sanger sequencing and compare the sequence to the normal gene to see if a mutation is present. To test the effect of the mutation, you would want to see if an active protein has been formed.
To see if a normal sized protein has been formed, you could perform a western blot, comparing the protein band to the WT protein band. If the protein is absent or much smaller, it is likely not a functional protein.
(2) epigenetic silencing at the promoter of the gene, resulting in reduced transcription.
To check for changes in the epigenetic landscape of the promoter, you could perform chromatin immunoprecipitation by extracting the chromatin from the tumour cells and using antibodies for different chromatin marks to see what has changed between the normal cells and the tumor cells. E.g. H3K9me3, H3K27me3. You would perform a pull down with the antibody of interest and then PCR for your promoter to specifically look at changes at that gene compared to normal cells. To test DNA methylation, you could perform bisulfite sequencing.
To see how transcription is affected, you could extract RNA from the tumor and normal cells, and compare the levels of RNA between the two samples by qRT-PCR
Agonists activate the receptor thereby <u>increasing</u> activity at the synapse while antagonists generally prevent agonists from activating the receptors thereby <u>decreasing</u> activity at the synapse.
- An agonist is the component that has the ability to increase the activity carried out by another substance.
- The agonists work from their faculty of coupling to a cell-type receptor, in this way, they manage to generate a certain action in the cell.
- The antagonists are the compounds that cause the opposite when they bind to the receptor, they cause a blockade by decreasing the activation of a synaptic receptor.
Therefore, we can conclude that agonists are compounds capable of increasing the action of synapse and blockers (antagonists) decrease activity at the synapse.
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