The answer is they "refused to ratify".
The League of Nations charter became part of the Treaty of Versailles following World War I. President Woodrow Wilson pushed hard for its passing, to the point that he earned the 1919 Nobel Peace Prize. However, when he brought the charter to the U.S. Congress, the members refused to ratify it. Thus, the international organization promoted by President Wilson never became a part of American politics.
Article Two of the United States Constitution establishes the executive branch of the federal government, which carries out and enforces federal laws. The executive branch includes the President, the Vice President, the Cabinet, executive departments, independent agencies, and other boards, commissions, and committees.
Unlike the trade routes of the the classical era, the Internet does not limit the extent to which items can be traded in a certain network--meaning that things can be traded between practically any two locations on the globe with an internet connection.