Question

An epidemiologic study examined the incidence of symptomatic Chlamydia infection in a cohort of 2000 young women in a county in Georgia over 5 years. All subjects were enrolled on the same day (Jan 1, 2015), and did not have Chlamydia infection at the time of study enrollment. During the study period, 440 subjects were newly diagnosed with Chlamydia infection. Subjects were followed for a total of 6200 person-years.
If no one dropped out of the study and no one developed Chlamydia infection during the study period, how many person-years would be contributed in total by subjects in this study?

Answer 1

a. If no one dropped out of the study and no one developed Chlamydia infection during the study period, the total number of person-years = 10,000 person-years (2,000 x 5 years).

What are person-years?

Person-years are the product of the number of people in a study and the amount of time each person spends in the study.

Thus, since there are 2,000 women in this study, who spend 5 years each, the person-years are 10,000 (2,000 x 5) person-years.

b. The estimated incidence rate of Chlamydia infection among women who participated in the study is 0.62 or 620 per 1,000 person-years (6,200/10,000).

What is an incidence rate?

An incidence rate describes the quickness of disease occurrence in a population. Since the incidence rate is based on person-time, it has some advantages over an incidence proportion, which measures the probability of developing a disease during the specified period.

Data and Calculations:

Sample of young women = 2,000

Period of study = 5 years

Subjects newly diagnosed with infection = 440

Total number of person-years of subjects diagnosed = 6,200

Thus, the total number of person-years in the study is 10,000 person-years, while the incidence rate is 620 per 1,000.

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