Loss of Rb, an important part of the G1-S transition checkpoint, can result in uncontrolled cell cycle progression and cancer. All of the following would mimic loss of Rb except constitutively active Ras GTPase activating protein. Correct answer: letter E.
Constitutively active Ras GTPase activating protein would not mimic loss of Rb, because it would not directly result in uncontrolled cell cycle progression.
<h3>What is Retinoblastoma (RB)?</h3>
Rb is an important tumor suppressor protein that works to inhibit cell cycle progression by preventing the activation of E2F transcription factors. Constitutively active Ras GTPase activating protein would not directly interfere with the Rb-E2F pathway, which is necessary for uncontrolled cell cycle progression and cancer.
Learn more about the cell cycle:
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F. b and c only the Sun is closer to the horizon <span> the Sun’s light is spread and diluted more</span>
In the case of liquid droplets, including water, surface tension is the factor, which is accountable for their shapes and configuration. Though can easily be malformed, the droplets of water seem to be pulled into a spherical shape due to the cohesive forces of the surface layer.
In the non-existence of other forces, involving gravity, the drops of almost all the liquids would be almost spherical.
