If the live enzyme fructose 1,6- bisphosphatase defect is occured and this results in an abnormally high levels of lactate in the blood plasme this will result into the lactate will accumulate into the blood.
What is the work of fructose 1,6-biphosphatase enzyme?
In the liver, gluconeogenesis converts lactate to glucose. If FBPase-1 is defective, lactate cannot enter the gluconeogenic pathway in hepatocytes, building up in the blood.
A crucial enzyme in gluconeogenesis is fructose 1,6-bisphosphatase (FBPase). It is a possible target for drugs used to treat type II diabetes. Additionally, the protein is linked to a rare genetic metabolic disorder, and certain cancer cells lack the activity of the enzyme FBPase, which encourages glycolysis and aids in the Warburg effect.
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The offspring are made to learn how to live on their own
If we cross a homozygous blue oval plant with a homozygous white round plant
P: BBrr x bbRR
The resulting F1 progeny:
F1: BbRr
If we cross BbRr with bbrr
F2: 1/4 blue round plants (250 plants) ¼ blue oval plants (250 plants) ¼ white round plants (250 plants) and ¼ white oval plants (250 plants).
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C) To increase our understanding of general principles