Answer:
the pathway will be under-expressed.
- the alpha subunit helps to bind with either GDP or GTP. when the α subunit is bound with GDP, it will be bound to β and γ subunits and thus forms an inactive state for G-protein.
- when the alpha subunit binds with the GTP, it becomes activated and dissociates β and γ subunits.
if G-protein Coupled Receptor is unable from dissociating β and γ subunits, then the pathway will go under expression.
The chemical qualities of the alpha subunit allow it to bind easily to one of two guanine subunits, GDP or GTP. The protein thus has two functional formations. When GDP is bound to the alpha subunit, the alpha subunit remains bound to the beta-gamma subunit to form an inactive trimeric protein.
G-proteins, cAMP, and Ion Channel Opening. The alpha subunit activates adenylate cyclase, in purple, and loses GTP. Adenylate cyclase converts ATP to cyclic AMP, which then activates Protein Kinase, shown in blue. Protein Kinase phosphorylates an ion channel, letting sodium ions rush into the cell.
As a result of the ligand binding to its site on the G-protein-linked receptor, A) the G-protein changes conformation and GTP replaces the GDP on the alpha subunit. ... Inactivation of the alpha subunit occurs when its own phosphorylase activity removes a phosphate from the GTP.
Answer:
A. The complementary shapes of an enzyme and a substrate
Explanation:
The Lock-and-Key model was made to show how an enzyme's active zone fits a substrate and how they bond together. It correlates just like a lock and a key; you have to have the correct-shaped key in order to open a lock. Same process of thought with the enzymes; you must have the same shape for both in order to bind together,
A cell membrane has consists of phospholipids. They are lipids with a phosphate group such as (PO3/4). They are hydrophilic meaning that they allow water to pass through proteins well some at least- but it might be needed to move molecules throughnthe membrane as well. But basically it's just a composed bilayer of phospholipids with hydrophobic acid tails so that they could all meet with one another. The form complexes into function to describe or to identify the cells to anothers cells.
Hope this helps.
Answer:
zero
Explanation:
Displacement is a vector, meaning that the direction is very important. Displacement is the distance from the starting point to wherever the object is. So a car that does a 500 m lap will have covered 500 m in distance but displacement is zero because, having come back to the starting point, the distance between the starting point and where the object is, is zero.
