Commas are used when listing 3 or more things and when adding details to something (like saying "Jennie, my little sister" or "Tom and Brent, my best friends").
The impact of mental health depression and anxiety in a local community in short term results in breathing problems, breathing rate increase, heart rate increases, increase in blood pressure, fatigue, shaking, dizziness.
The long term impact due to mental depression and anxiety local community can result in a disastrous effect on physical health and mental health and also lead to death.
