Question

Why does one strand of DNA need to be copied in short fragments?

Answer 1

Why does one strand of DNA need to be copied in short fragments?

• Because the two strands of a DNA molecule have complementary base pairs

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Answer 2

Because DNA polymerase can only synthesize DNA in a 5′ to 3′ direction, the other new strand is put together in short pieces called Okazaki fragments. The Okazaki fragments each require a primer made of RNA to start the synthesis. The strand with the Okazaki fragments is known as the lagging strand.

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