Answer: The core of a topic, the facts that make the topic
A person that is uncool or not popular.
The wording to this question is a little confusing.
detrimental well being since detrimental means to causing harm. But i believe that you mean what are two factors to a well being in a relationship. In that case: 1. good communication, that is very important in all types of relationships.
2. would be trust, and the ability to relay on the other for support and vice versa