The laws of thermodynamics are important unifying principles of biology. These principles govern the chemical processes (metabolism) in all biological organisms. The First Law of Thermodynamics, also known as the law of conservation of energy, states that energy can neither be created nor destroyed. It may change from one form to another, but the energy in a closed system remains constant.
"An allele is a variant form of a gene. Genes come in different varieties, called alleles. Somatic cells contain two alleles for every gene, with one allele provided by each parent of an organism."- Nature .com
