1.be (a part) of a whole.
"single parents constitute a great proportion of the poor"
synonyms: amount to, add up to, account for, form, make up, compose, comprise, represent
"farmers constituted 10 percent of the population"
2.
give legal or constitutional form to (an institution); establish by law.
synonyms: inaugurate, initiate, establish, found, create, set up, put in place, start, begin, originate, form, organize, develop, shape; More
Answer:
Tobacco use is the single most preventable cause of disease, disability, and death in the United States.
Answer:
the last one i think hope this helps