Question

Two unlinked loci affect mouse fur color. nn or nn mice are agouti. mice with genotype nn are albino because all pigment production is blocked, regardless of the phenotype at the second locus. at the second locus, the a allele (agouti coat) is dominant to the a allele (black coat). what would be the result of a cross between two agouti mice of genotype nnaa?

Answer 1

The result of a cross between two agouti mice of genotype nnaa are albino offspring because mice with genotype nn are albino (pigment production is blocked by epistasis).

What is epistasis?

Epistasis is a genetic phenomenon where the presence of a gene variant alters a phenotype influenced by other genes.

A gene is epistatic when a variant (allele) can alter the expression of another gene in the same signaling pathway.

Epistatic interactions are very common in nature and many traits are influenced by this type of interaction.

Learn more about epistasis here:

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