Answer:
George washington was the first president of United States
The amendment becomes part of the Constitution when it has been ratified by three-fourths (currently 38) of the states. This process has been used for ratification of every amendment to the Constitution thus far. Article V also provides for an alternative process, which has never been utilized.
The first known pandemic was the Plague of Justinian, which took place in the Byzantine Empire in A.D. 542, it struck its capital Constantinople, part of the Sassanian Empire in the Middle East and several cities across the Eastern Mediterranean Sea. Modern scholars think it started in Central Asia.