So if we take 1/4 to be the 100%, what is 2/3 in percentage off of it then?

yes, is a large value, because 2/3 is indeed larger than 1/4, more than twice as large.
The answer is y=4/3. Hope this helps.
I think this is the Answer
8.235*10^-4
220miles / 4 hours = 55 miles/hr
55mi/hr x 7hrs = 385 miles