They got into a major confrontation with the confederates.
Explanation:
The 6th Massachusets became the first union unit to take casualties in action on April 19th, 1861.
The Sick man of Europe<span> was a label given to a </span>European country<span> who were experiencing a time of difficulty or impoverishment. This term was first used in the mid-19th century to describe the </span>Ottoman Empire.
The answer to you question is: Minoan civilization
I believe it's candidates :)
By the United States in March 4, 1789