Answer:
Severe neck stiffness or pain.
Confusion or extreme irritability.
Extreme sleepiness.
Persistent nausea or vomiting.
Severe sensitivity to light (photophobia).
Explanation:
Answer:
Okay
Explanation:
Human topoisomerase I plays an important role in removing positive DNA supercoils that accumulate ahead of replication forks. It also is the target for camptothecin-based anticancer drugs that act by increasing levels of topoisomerase I-mediated DNA scission. Evidence suggests that cleavage events most likely to generate permanent genomic damage are those that occur ahead of DNA tracking systems. Therefore, it is important to characterize the ability of topoisomerase I to cleave positively supercoiled DNA. Results confirm that the human enzyme maintains higher levels of cleavage with positively as opposed to negatively supercoiled substrates in the absence or presence of anticancer drugs. Enhanced drug efficacy on positively supercoiled DNA is due primarily to an increase in baseline levels of cleavage. Sites of topoisomerase I-mediated DNA cleavage do not appear to be affected by supercoil geometry. However, rates of ligation are slower with positively supercoiled substrates. Finally, intercalators enhance topoisomerase I-mediated cleavage of negatively supercoiled substrates but not positively supercoiled or linear DNA. We suggest that these compounds act by altering the perceived topological state of the double helix, making underwound DNA appear to be overwound to the enzyme, and propose that these compounds be referred to as ‘topological poisons of topoisomerase I’
Answer:
right answer is option no c cardiology
The left side of the heart is responsible for receiving blood from the pulmonary circuit from the lungs. So failure of it leads to increased pressure in the lungs (pulmonary circuit). That would cause the right side of the heart, which pumps blood to the lungs) to exert more force to keep blood moving through the pulmonary circuit.
Hope it helps!
Answer:
The correct answer is A
Explanation:
There are several respiratory centers, the main ones are in the medulla oblongata, also called spinal bulb, image attachment so you can observe better.
Image Reference:
https://en.wikipedia.org/wiki/Respiratory_center
