Answer:
Depends on the kind of interaction the alleles have with each other.
Dominant, co dominant or incomplete dominant
 
        
                    
             
        
        
        
Perhaps the most significant factor that affects the biogeochemical cycles in the terms of human involvement is global warming, which disrupts natural cycles on various levels. 
        
                    
             
        
        
        
It would be major depending on the interval but also minor so true