An agonist is a drug that binds to the receptor, producing a similar response to the intended chemical and receptor. Whereas an antagonist is a drug that binds to the receptor either on the primary site, or on another site, which all together stops the receptor from producing a response
It is better to break a bone than tear a muscle as bones have more blood supply to them than ligaments/tendons. Ligaments/tendons are also more complex to rebuild. In general, wounds heal slower when blood cannot circulate properly.