Answer:
A mutation in Ras protein which will cause hyperactivity will eventually lead to cancer.
Explanation:
Ras protein was first discovered in Rous sarcoma virus (RSV) and it is a proto-oncogene product. In normal conditions, it plays an important role in cellular signalling but in case of gain of function/hyperactivity it gets converted into cellular oncogene. In several types of cancers a point mutation has been reported in Ras protein.
Just like G protein, it is also a GTPase switch protein but unlike G protein which is trimeric, it is monomeric. In the plasma membrane, it is attached with the help of lipids like prenyl or palmitoyl groups. During signal transduction pathway when it gets activated, it downstream activates MAPK pathway and causes gene expression but when it gets hyperactivated it causes over expression of genes leading to cancer.
Answer:
The genetic variations that are best suited for their enviornment
Explanation:
Those that are not well suited for their environment will die off, leaving only the ones that are suited for it. This species will slowly take hold until the species has adapted and become a completely different one.
Answer:
Average annual temperature in US cities would range between 50-70 degrees Fahrenheit
Explanation:
There are several factors that can influence the temperature of city in general. Higher altitude has a lower temperature because it has less air density and absorbs less sunlight. The city latitude coordinate also determines how much sunlight they will get. The closer the city to the equator, the more sunlight they can get.
Distance to the sea will influence the rate of rainfall and also influence temperature. Ocean currents can move hot water from other regions too.
