Question

Beta adrenergic receptor-blocking drugs are often called beta-blockers. These drugs prevent the hormone epinephrine from binding to its G-protein-coupled receptor. In the pathway activated by epinephrine, the activated G-protein would normally activate adenylate cyclase. When the drug is in use, which step(s) is/are prevented

Answer 1

All the steps of GPCR signaling would be prevented in the presence of a beta-blocker drug.

What is Beta-blocker?

Beta-blocker may be defined as a kind of medication that chokes the activity of substances, such as adrenaline, on nerve cells and provokes blood vessels to relax and dilate.

Adrenergic receptors choke the attachment of catecholamine that is epinephrine to the G-protein. G-protein activates adenylyl cyclase which in turn activates protein kinase A.

But when the beta-blocker drug is subjected to this pathway, it blocks the attachment of the hormone to their receptors, hence none of the pathway or steps would be carried forward. This is because signaling is not initiated.

Therefore, all the steps of GPCR signaling would be prevented in the presence of a beta-blocker drug.

To learn more about GPCR signaling, refer to the link:

brainly.com/question/9882354

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