Question

____ produce their effect by preventing an enzyme from breaking down serotonin and norepinephrine, thereby _____ the availability of the neurotransmitter in the synapses.\

Answer 1

Answer:

Monoamine oxidase inhibitors produce their effect by preventing an enzyme from breaking down serotonin and norepinephrine, thereby increasing the availability of neurotransmitters in the synapses.

Explanation:

Monoamine oxidase inhibitors or MAOIs are strong antidepressants used to treat depression and bipolar disorders. Some drug formulations are isocarboxazid, selegiline, tranylcypromine, etc. They work by blocking the enzyme that breaks down neurotransmitters like serotonin, norepinephrine, and dopamine.  

The enzyme monoamine oxidase removed neurotransmitters from the brain but the drug MAOI suppresses the action of the enzyme. This increases the availability of neurotransmitters in the synapses. The increased levels of neurotransmitters work on the cells in the region of the brain affected by depression.

Learn more about MAOIs here:

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