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svlad2 [7]
2 years ago
6

Explain why translesional synthesis is a DNA damage tolerenace mechanism rather than a DNA repair mechanism?

Medicine
1 answer:
kolezko [41]2 years ago
5 0

Proof Reading: while printing a page, the typesetter set the types and impression is taken, proofreading is done to correct mistakes if any, and the final printing is done. A similar follow-up mechanism is done after DNA synthesis. If DNA polymerase detects an incorrect nucleotide pair, it will remove and replace with the correct nucleotide immediately.

<h3>What is Mismatch Repair?</h3>

Mismatch Repair:even after DNA synthesis, mismatch area(insertion or deletion) can be identified on the newly synthesized DNA.

In the mismatch repair, specific proteins scan the newly synthesized DNA strand. The mismatch area is identified and loop.

The second protein complex remove the mismatch segment. Finally correct segment is synthesized by the help of DNA polymerase, SSBs and ligase.

DNA damage repair mechanism: when DNA get damaged, there's a repair process that fix the damage. This includes Direct reversal, excision repair and Double-stranded break repair.

Thus, this could be the answer.

To learn more about DNA click here:

brainly.com/question/264225

#SPJ1

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2 years ago
Diabetes insipidus results in the formation of vast quantities of dilute urine. This disease is the result of a disorder regardi
Ksenya-84 [330]

Answer: Diabetes Insipidus

Medical Condition

Image for Condition

A condition that results from an imbalance of water in the body. This causes extreme thirst, and frequent excessive urination.

How common is condition?

Very rare (Fewer than 20,000 cases per year in US)

Does diagnosis require lab test or imaging?

Often requires lab test or imaging

Is condition treatable?

Treatments can help manage condition, no known cure

Time taken for recovery

Can be lifelong

Diabetes insipidus is a hormonal disorder that results from decreased levels of anti-diuretic hormone (ADH), also known as vasopressin. This hormone reduction leads to reduced retention of water in the body. Commonly noted symptoms include severe thirst, and frequent, excessive urination. Medications and lifestyle changes are the main course of treatment. Treatment options are decided based on the type of diabetes insipidus.

Symptoms

Common symptoms include:

Severe thirst

Frequent urination where excessive diluted urine is excreted

Bed-wetting

Fussiness or inconsolable crying in children

Trouble sleeping

Fever

Vomiting

Diarrhea

Delayed growth

Weight loss

Treatments

Medications and lifestyle changes are the main course of treatment. Treatment options are decided based on the type of diabetes insipidus.

Medication

Hormone therapy: Taken as nasal spray, oral tablets, or injections, these are synthetic forms of ADH given to reduce the frequency of urination.

Desmopressin

Self care

Adequate water intake to avoid dehydration.

Reduce salt intake.

Avoid medications that increase urine output, after consultation with your doctor.

Avoid activities that cause dehydration.

Wear a medical alert badge or bracelet.

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