Disruption in the intercalated discs in the cardiac muscles would interfere with the hearts ability to beat in synchronous manner.
The important salient features of intercalated disc are-
These intercalated disc in cardiac muscles of the heart create connections between nearby cells
The intercalated disc provides for coordinated operation of the cardiac cells and is highly specialised to facilitate the beating
Extensive folds and intercellular junctions for mechanical and electrical interactions between neighbouring cells make up the intercalated disc at the ends of muscle cells
The electrical characteristics of the cardiac muscle cells and the passage of electrical information from one region of the heart to another determine the rate at which the heart contracts and the synchronisation of atrial and ventricular contraction necessary for the efficient pumping of blood.
