Question

Of the following choices, what is the approximate LD50 of the least toxic substance? 20 mg/kg, 70 mg/kg, or 130 mg/kg

Answer 1

The approximate LD50 of the least toxic substance will be 130 mg/Kg.

• The dose necessary to cause the death of 50% of a population under test after a predetermined test period is known as the LD50 value for a drug.
• Commonly used as a broad indicator of a substance's acute toxicity are LD50 values.
• Greater toxicity is indicated by a lower LD50. A low LD50 of 500 mg/kg or less implies severe toxicity.
• Moderate toxicity is indicated by an LD50 of 500 to 1,000 mg/kg. A modest toxicity level of 1,000 to 2,000 mg/kg is indicated.
• The species is especially vulnerable to the poison if the LD50 is low. The lethal dose (LD50) of a specific poison might change significantly between several animal species.
• Thus out of all the options, LD50 130 mg/kg will have the lowest toxicity and 20 mg/kg will be the highest.

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