Dimenhydrinate: This antihistamine is an effective treatment for motion sickness, but should not be given to children 2 or younger.
Diphenhydramine: This antihistamine is effective in relieving nausea and dizziness.
What is motion sickness caused by?
Your brain senses movement by getting signals from your inner ears, eyes, muscles, and joints.
When it gets signals that do not match, you can get motion sickness.
For example, if you are reading on your phone while riding a bus, your eyes are focused on something that is not moving, but your inner ear senses motion.
What is the best prescription motion sickness medicine?
Medications
Scopolamine (Transderm Scop). Most commonly prescribed medication for motion sickness.
Promethazine (Phenergan). Administered 2 hours before travel.
Cyclizine (Marezine). Works best when taken at least 30 minutes before travel.
Dimenhydrinate (Dramamine). Take every 4 to 8 hours.