1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
MakcuM [25]
2 years ago
12

Phenytoin blocks the opening of voltage-gated na channels in neurons. therefore, this action has its primary effects on which pa

rt of the neuron?
Biology
1 answer:
dusya [7]2 years ago
7 0

Numerous antiepileptic medications, such phenytoin, have been designed to block voltage-gated sodium channels (VGSC) in neuronal membrane. In addition, multiple toxins and pharmacological modulators work by attaching to various biophysical states of the VGSC to cause their effects.  Depending on how modulatory agents act, some VGSC states are stabilized or destabilized, altering the channel's biophysical properties. The first anticonvulsant to successfully treat epileptic disorders without causing undesirable side effects such as brain drowsiness was phenytoin.

Phenytoin has been indicated to block high-frequency neuronal activity potentials from the inner vestibule of the pore, as demonstrated by electrophysiological research and site-directed mutation.

Frequency and voltage both affect phenytoin binding.

There are theories that phenytoin interferes with the late sodium current that sustains depolarizations in epilepsy by blocking non-inactivated channels.

To learn more about phenytoin click here

brainly.com/question/13386639

#SPJ4

You might be interested in
Pls help idk pls help :)
RideAnS [48]
Through the exosphere
7 0
3 years ago
One difference between plants and animals is that plants are?
kumpel [21]
Plants are in the ground with soil
7 0
2 years ago
Read 2 more answers
50 Points - URGENT, please help!
makvit [3.9K]
The table is this and its a 1/4 chance

8 0
3 years ago
Read 2 more answers
Is a crab a vertebrate or invertebrate?
Flauer [41]
Invertebrate, b/c it doesn't have a spine of any kind 

6 0
3 years ago
If a bird eats a mouse that eats grass, the bird is a(n)
Studentka2010 [4]

Answer:

First level consumer

Explanation:

First level consumers eat plants eat producers that make their own food, therefore making the mouse a first level or primary consumer.

4 0
2 years ago
Other questions:
  • What is the main reason that energy is harvested in stages in cellular respiration?
    14·1 answer
  • A ship is at anchor. Over its side hangs a rope ladder with rungs a foot apart. The
    10·1 answer
  • Name the 3 parts of a nucleotide
    10·1 answer
  • What is produced in a lymph node
    7·2 answers
  • Can someone please answer all these questions?
    15·1 answer
  • What is produced by cellular respiration?
    6·2 answers
  • Use the diagram below to answer the question photosynthesis cellular respiration energy in energy in energy out energy out
    11·2 answers
  • ​ Why do all cells in the body need oxygen?​​
    5·1 answer
  • ATP synthase is powered or driven by ______ flowing through it, in order to make ATP molecules.
    15·1 answer
  • Vaccines are
    12·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!