1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
MakcuM [25]
2 years ago
12

Phenytoin blocks the opening of voltage-gated na channels in neurons. therefore, this action has its primary effects on which pa

rt of the neuron?
Biology
1 answer:
dusya [7]2 years ago
7 0

Numerous antiepileptic medications, such phenytoin, have been designed to block voltage-gated sodium channels (VGSC) in neuronal membrane. In addition, multiple toxins and pharmacological modulators work by attaching to various biophysical states of the VGSC to cause their effects.  Depending on how modulatory agents act, some VGSC states are stabilized or destabilized, altering the channel's biophysical properties. The first anticonvulsant to successfully treat epileptic disorders without causing undesirable side effects such as brain drowsiness was phenytoin.

Phenytoin has been indicated to block high-frequency neuronal activity potentials from the inner vestibule of the pore, as demonstrated by electrophysiological research and site-directed mutation.

Frequency and voltage both affect phenytoin binding.

There are theories that phenytoin interferes with the late sodium current that sustains depolarizations in epilepsy by blocking non-inactivated channels.

To learn more about phenytoin click here

brainly.com/question/13386639

#SPJ4

You might be interested in
A single pair of goldfish in an aquarium produced a large number of offspring. These offspring showed variations in body shape a
vagabundo [1.1K]
The most likely explanation for the variation is the offspring were produced from different combination of genes. A single pair of gold fish mentioned in the question means a male and a female gold fish. The two of them mated and contributed different genes to the fertilized fish eggs, this results in production of various body shape and colouration which is known as variation.
4 0
3 years ago
Do you consider scientific truth as objective and universal? Explain your answer.
Irina18 [472]

Explanation:

Tahukah kamu, mengapa motor berhenti di depan lampu merah?

karena motornya direm. Coba kalau nggak direm bisa bahaya tuh.

Tebak binatang apa yang jago renang?

Bebek. Kalau ikan bukan renang tapi menyelam

Kenapa di rel kereta api ditaruh batu?

Soalnya kalau ditaruh duit nanti pada diambil.

5 0
3 years ago
2. If a star's spectral lines are shifted t longer wavelengths (redshift) the star is moving_______Earth.
Neporo4naja [7]
A) toward the earth  ...hope this hlep
8 0
3 years ago
Pablo wants to enter the science fair. Which question could be answered through scientific investigation?
Ipatiy [6.2K]
I believe the answer is D
3 0
3 years ago
Read 2 more answers
Read the paragraphs and answer the question that follows.
Artemon [7]
We can infer of the two paragraphs that Geological movements are often hazardous when they happen quickly, and that the movement of plate boundaries does not always cause disaster.

The excerpt is telling us that "the <span>earthquakes caused a lot of damage, as well as dramatic changes to the local ecosystem", which is supporting the conclusion: "geological movements are often hazardous when they happen quickly." 
But is also telling us that "</span>The slip caused several rock formations and structures to develop cracks. However there was no large-scale disaster or disruption.", which is supporting the conclusion:  the movement of plate boundaries does not always cause disaster."
4 0
3 years ago
Read 2 more answers
Other questions:
  • Kendal realized that the principal of probability could be used to
    11·1 answer
  • In osseous tissue, blood vessels and nerves are found in the
    9·1 answer
  • The target blood pressure for a trauma patient with suspected intraabdominal hemorrhage is :
    8·1 answer
  • _____ is an unpleasant side effect that alcohol withdrawal creates for an alcoholic. excessive sleepiness leptokurtic reaction c
    9·1 answer
  • How to remember the different prokaryotic and eukaryotic
    7·1 answer
  • Ribosomes are the site where are produced.
    10·2 answers
  • How would temperature affect sound in the ocean?
    7·1 answer
  • Just do the first one and if you don’t know it don’t answer please this is due today
    15·1 answer
  • Down's Syndrome is also called Trisomy 21 because affected people have three copies of chromosome 21. How is this possible?
    11·1 answer
  • Which of the following organisms can only use behavioral controls to maintain its body temperature?
    10·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!