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MakcuM [25]
2 years ago
12

Phenytoin blocks the opening of voltage-gated na channels in neurons. therefore, this action has its primary effects on which pa

rt of the neuron?
Biology
1 answer:
dusya [7]2 years ago
7 0

Numerous antiepileptic medications, such phenytoin, have been designed to block voltage-gated sodium channels (VGSC) in neuronal membrane. In addition, multiple toxins and pharmacological modulators work by attaching to various biophysical states of the VGSC to cause their effects.  Depending on how modulatory agents act, some VGSC states are stabilized or destabilized, altering the channel's biophysical properties. The first anticonvulsant to successfully treat epileptic disorders without causing undesirable side effects such as brain drowsiness was phenytoin.

Phenytoin has been indicated to block high-frequency neuronal activity potentials from the inner vestibule of the pore, as demonstrated by electrophysiological research and site-directed mutation.

Frequency and voltage both affect phenytoin binding.

There are theories that phenytoin interferes with the late sodium current that sustains depolarizations in epilepsy by blocking non-inactivated channels.

To learn more about phenytoin click here

brainly.com/question/13386639

#SPJ4

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Compare and contrast the structure of the sun with that of the Earth
Arada [10]

Structure of Sun:

The sun has six layers.

Three layers named as

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The other three layers namely

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Comprises the inner layer or part of sun that are not seen.

Structure of earth:

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8 0
3 years ago
Who proposed that the structure of DNA is a double helix
artcher [175]
James D Watson and Francis Crick
6 0
3 years ago
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Suppose a fern fossil is found between layer Y and layer z during which time range with fern fossil most likely have formed?
Snowcat [4.5K]

Answer: C. 30 - 50 million years ago

Explanation:

Fossils found in layer Y formed 30 million years ago according to the graph above. Similarly, fossils found in layer Z formed 50 million years ago.

If a fossil (fern fossil) is found between layer Y and layer Z, it means that it formed between the years that the fossils in layers Y and Z formed which is 30 - 50 million years ago.

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3 years ago
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6 0
2 years ago
if the following mRNA strand were produced during transcription what amino acids would be found in the protein GGCUACGGGCAUCAC
ioda

The correct answer to your question is B. Glycine-Tyrosine-Glycine-Histidine-Histidine.

You can find this by taking groups of codons starting with the first group (GGC). GGC is located under Glycine so Glycine will therfore be an amino acid found in the protein. Continue doing this with the next codons to come up with the answer.

I hope this isn't too late and still helps!

:)

4 0
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