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MakcuM [25]
1 year ago
12

Phenytoin blocks the opening of voltage-gated na channels in neurons. therefore, this action has its primary effects on which pa

rt of the neuron?
Biology
1 answer:
dusya [7]1 year ago
7 0

Numerous antiepileptic medications, such phenytoin, have been designed to block voltage-gated sodium channels (VGSC) in neuronal membrane. In addition, multiple toxins and pharmacological modulators work by attaching to various biophysical states of the VGSC to cause their effects.  Depending on how modulatory agents act, some VGSC states are stabilized or destabilized, altering the channel's biophysical properties. The first anticonvulsant to successfully treat epileptic disorders without causing undesirable side effects such as brain drowsiness was phenytoin.

Phenytoin has been indicated to block high-frequency neuronal activity potentials from the inner vestibule of the pore, as demonstrated by electrophysiological research and site-directed mutation.

Frequency and voltage both affect phenytoin binding.

There are theories that phenytoin interferes with the late sodium current that sustains depolarizations in epilepsy by blocking non-inactivated channels.

To learn more about phenytoin click here

brainly.com/question/13386639

#SPJ4

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Which of the following statements correctly describes any chemical reaction that has reached equilibrium?
Vesnalui [34]

Answer:

Option (d).

Explanation:

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Chemical equilibrium may be defined as the equilibrium in which the reactants and products concentration remains constant with time. The rate of the backward reaction is equal to the rate of forward reaction.

Thus, the correct answer is option (d).

8 0
2 years ago
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BigorU [14]

Answer:

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Hope this helped

3 0
2 years ago
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Galina-37 [17]

Answer:

Parasympathetic nervous system effects are slow or inhibit function, where is sympathetic, is responsible for the intense physical activity.

Explanation:

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Thus, the comparison of these nervous systems is mention above.

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7 0
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Zielflug [23.3K]
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