According to the guide, housing is recommended preferentially for domesticated rodents is Solid bottom cages with contact bedding.
Mice, rats, squirrels, prairie dogs, porcupines, beavers, guinea pigs, and hamsters are examples of well-known rodents. They have a single pair of incisors that are continuously growing in both the upper and lower jaws.
Rodents may prefer solid-bottom caging with bedding, according to some studies. Rodents should therefore be housed in solid-bottom cages with bedding, according to the Guide for the Care and Use of Laboratory Animals, which also notes that animals "should be provided with adequate bedding substrate and/or structures for resting and sleeping" .
While these recommendations have sparked a transition away from wire-mesh cages and toward plastic cages as well as the requirement for a substrate to support resting and thermoregulation, there are few unbiased reports comparing the effectiveness of these caging accommodations to their wire-mesh forebears.
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