Question

Post a discussion of pharmacokinetics and pharmacodynamics related to anxiolytic medications used to treat GAD. In your discussion, utilizing the discussion highlights, compare and contrast different treatment options that can be used.

Answer 1

In terms of the pharmacokinetics and pharmacodynamics of anxiolytics, they are typically antidepressants that affect the brain's neurotransmitters.

What are Pharmacokinetics and  Pharmacodynamics?

• Pharmacokinetics, commonly referred to as "what the body does to a medication," is the study of how drugs flow through the body, including how quickly they are absorbed, distributed, metabolized, and excreted.

• Pharmacodynamics is the study of the biochemical, physiological, and molecular effects of medications on the body and involves receptor binding (including receptor sensitivity), post receptor effects, and chemical interactions. It is frequently referred to as what a drug does to the body.

Americans frequently suffer from generalized anxiety disorder (GAD) in the United States. Around 265 million individuals worldwide suffer from anxiety disorders, according to the World Health Organization (2017).

• Medication to treat anxiety disorders, such as anxiolytics, is a subject of ongoing research.
• To relieve mood and anxiety symptoms, the drugs make sure that synapses are firing. There are other medicines that can be used to treat anxiety but are not anxiolytics.

Below are Various Treatment Options that can be used:

What are Antidepressants and Antihistamines?

• Antidepressants are frequently used concurrently to treat depression and anxiety in addition to treating anxiety.
• GAD can be effectively treated with antidepressants. There is evidence that GAD can be successfully treated with selective serotonin reuptake inhibitors (SSRIs), such as paroxetine, sertraline, citalopram, and escitalopram.

• Antihistamines offer calming effects that can reduce anxiety. Although Benadryl is most typically used as an antihistamine to treat allergies, it can also be used as a mild anxiolytic and antiemetic.

• Antihistamine hydroxyzine is frequently provided on an as-needed basis to patients who complain of anxiety. If administered late enough, this medicine is quite helpful and aids the patient in getting a decent night's sleep.

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