Question

Secondary lymphoid organs, such as the lymph nodes, spleen, and mucosa-associated lymphoid tissues, each have distinct features that are important for their role in initiating immune responses focused on different anatomical compartments (i.e., the peripheral tissues, the blood, or the gastrointestinal tract, respectively). Yet these organs share some overall structural features, such as distinct

Answer 1

One major difference between these secondary lymphoid organs is the mechanism by which antigens or pathogens enter the organ.

Naive T cells can develop into effector and memory T cells, which remove the triggering antigen in peripheral tissues and produce protective immunity, with the help of secondary lymphoid tissues.

The spleen, which collects bloodborne antigens, the lymph nodes, which deal with antigens found in peripheral tissues, and the mucosa-associated, bronchial-associated, and gut-associated lymphoid tissues where antigens from epithelial surfaces are collected are examples of secondary lymphoid organs.

Therefore, One major difference between these secondary lymphoid organs is the mechanism by which antigens or pathogens enter the organ.

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