The most patients with typical GBS present with rapidly progressive bilateral leg weakness with hypo/areflexia in the affected limbs. In rare cases, patients can present with facial, oculomotor, bulbar, i.e. difficulty with swallowing and speaking, weakness, or primary sensory symptoms.
The clinical diagnosis of GBS needs to be confirmed by cerebrospinal fluid analysis and nerve conduction studies. Lumbar puncture is indicated in every case of suspected GBS.
The things to be monitor in Guillain-Barré syndrome (GBS) respiratory status of patients with GBS must therefore be carefully and frequently monitored. Pulse oximetry and blood gases are inadequate for early detection of failure because hypoxemia and hypercarbia are very late manifestations.
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