The synthesis of fatty acids starts with a preparratory phase in which acetyl CoA is translocated from mitochondria to the cytosol. However, it cannot pass through the membrane, so it is translocated as citrate that is cleaved to acetyl CoA and oxaloacetate.
In the cytosol, acetyl CoA is transformed to malonyl-CoA, that is, a three carbon compound. Fatty acid synthesis starts with the transfer of the acetyl group from acetyl-CoA to fatty acid synthase.
Two-carbon groups supplied by malonyl-CoA, are supplemented to the developing acyl chain in a series of steps involving condensation, reduction, and dehydration reactions. Elongation of the fatty acid chain ceases at 16 carbon atoms, after 7 cycles, as the free fatty acid is discharged.
Answer:
There are not too many disadvantages of endoskeleton .
This is why most large animal around have them.
one large animal has one of the vunerability animals face without exoskeleton.
Explanation:
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