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Ivanshal [37]
2 years ago
7

Hexokinase, phosphofructokinase and pyruvate kinase are each subject to ________ control.

Medicine
1 answer:
xxTIMURxx [149]2 years ago
6 0

<u>Hexokinase, phosphofructokinase and pyruvate kinase are each subject to </u><u>Allosteric </u><u>control.</u>

What is significant about the enzymes phosphofructokinase and hexokinase?

  • The following key aspects of glycolysis are covered: Using the power of ATP, an enzyme known as hexokinase converts glucose into glucose-6-phosphate by adding a phosphate group.
  • Similar to this, an enzyme known as phosphofructokinase uses ATP to modify fructose-6-phosphate into fructose-1,6-diphosphate by adding a phosphate group.

<u>Allosteric Enzyme - </u>

An allosteric enzyme is an enzyme that contains a region to which small, regulatory molecules ("effectors") may bind in addition to and separate from the substrate binding site and thereby affect the catalytic activity.

What is a allosteric effect?

The binding of a ligand to one site on a protein molecule in such a way that the properties of another site on the same protein are affected.

Learn more about Allosteric Enzyme

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Explanation:

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3 years ago
Tsu LV, Dienes JE, Dager WE. Vitamin K dosing to reverse warfarin based on INR, route of administration, and home warfarin dose
lianna [129]

Subsequent INR readings are influenced by the dose, method, and initial INR of vitamin K. For intravenous vitamin K doses of 2 mg or more, INR decrease is comparable. FFP preadministration has no effect on INR readings 48 hours or more after vitamin K administration.

What is Abstract of Vitamin K dosing to reverse warfarin based on INR, route of administration, and home warfarin dose in the acute/critical care setting?

  • Commonly, vitamin K is used to reverse the anticoagulant effects of warfarin. The ideal vitamin K dosage and delivery method that does not lengthen bridging therapy are still unclear.
  • To ascertain the elements affecting the level and pace of vitamin K-induced INR reversal in the acute/critical care setting.
  • 400 patients' charts from between February 2008 and November 2010 who got vitamin K to counteract the effects of warfarin were examined. International normalized ratios (INRs), intravenous or oral vitamin K doses, and whether or not fresh frozen plasma (FFP) was administered were among the information gathered. INRs were measured 12, 24, and 48 hours before vitamin K treatment.
  • At baseline, 12 hours, 24 hours, and 48 hours, respectively, intravenous vitamin K decreased INR more quickly than oral vitamin K (5.09, 1.91, 1.54, and 1.41 vs. 5.67, 2.90, 2.14, and 1.58). Subsequent INR values were impacted by baseline INR (p 0.001), method of administration (p 0.001), and vitamin K dosage (p 0.001). For intravenous vitamin K doses of 2 mg or more, there was a similar drop in INR. Home warfarin dose had no effect on INR responses to intravenous or oral vitamin K (p = 0.98 and 0.27, respectively). FFP had no effect on INR readings 48 hours later. Although larger vitamin K doses and longer anticoagulation bridge therapy appeared to be related, neither the incidence (p = 0.63) nor the duration (p = 0.61) were statistically significant.

To learn more about vitamin K doses visit:

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7 0
2 years ago
What technique was used to visualize the fingerprint relevant to the Madrid case and what are its limitations?
omeli [17]

Answer:

En 1892, su método sirvió para resolver, por primera vez en la historia, un homicidio mediante evidencia de huellas dactilares en la escena del crimen. Los hijos de una mujer llamada Francisca Rojas habían sido asesinados, y ella misma había señalado como responsable a un hombre al que había rechazado como marido. Los agentes de policía no lograron arrancarle una confesión al sospechoso aun sometiéndolo a torturas, así que se pusieron a investigar a fondo y encontraron una huella ensangrentada en una puerta.

Al cotejarla, descubrieron que la asesina no era otra que la madre, que, ante la evidencia, acabó confesando. El jefe de la Policía no tardó en adoptar oficialmente el Sistema Dactiloscópico Argentino, como posteriormente se conocería, lo que convirtió a Argentina en el primer país en depender únicamente de las huellas dactilares como método de identificación. A principios del siglo XX, el sistema de Vucetich empezó a difundirse por todo el mundo.

Explanation:

7 0
3 years ago
Decreased estrogen levels allow osteoclasts to remain active beyond their normal lifespan. Based on this information, which of t
PSYCHO15rus [73]

Answer:

Decreased bone density and increased calcium in the blood

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3 years ago
Pathogens multiply at a rapid rate within what temperature range?
Tomtit [17]

Answer:

41° F and 135° F (5°C and 57° C)

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