The answer to this is D. Bile is used mainly as a digestive substance to metabolize oils and fats.
Hypertension or the unhealthy increase in blood pressure means that the blood is working harder to pump blood throughout the systemic vasculature, which although may not seem that base is actually pretty bad. Patient with uncontrolled HTN are at increased risks of artery wall weakening and damage causing dangerous dilation called Aneurysms, which if blown can lead to very quick bleeding out. The heart will continue pumping, however eventually you will have progressed to the point where your heart will not be able to pump efficiently and it will begin to fail.
I'm not 100% sure if this is the answer but it makes sense. The body is dependent on the drug to make it feel 'normal' So it would be physical dependence because obviously, the body is dependent on that drug. That's basically what withdrawals are.