In cases of acute renal failure, serum creatinine (SCR) and blood urea nitrogen (BUN) incorrectly predict the glomerular filtration rate (GFR). The possibility exists for serum cystatin C (CYS) to be a more accurate GFR marker. In order to examine the sensitivity of SCR, BUN, and CYS in identifying acute renal failure in mice, this study was conducted.
The conclusion of the study was that In mouse models, CYS can be utilized as an accurate and dependable marker for renal function. In comparison to SCR and BUN, CYS is more sensitive and detects kidney impairment early.
<h3>What is
glomerular filtration rate (GFR)?</h3>
A blood test called a glomerular filtration rate (GFR) measures how well your kidneys are functioning. Glomeruli are little filters found in your kidneys. These filters aid in clearing the blood of waste and extra fluid. How much blood flows through these filters each minute is determined by a GFR test.
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