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2 years ago

Patient-reported outcomes in ZUMA-7, a phase 3 study of axicabtagene ciloleucel in second-line large B-cell lymphoma

1 answer:

5 0

The first comparison of PROs with axi-cel, an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy, to SOC as second-line treatment (Tx) in relapsed/refractory (R/R) LBCL in the pivotal Phase 3 ZUMA-7 project.

According to ZUMA-7, the first randomized, international, multicenter Phase 3 study comparing axi-cel to SOC in second-line R/R LBCL, axi-cel treatment results in a clinically significant improvement in QoL at D100 when compared to SOC as determined by many recognized PRO tools. In the SOC arm, in particular, score comparisons at later timepoints call for cautious interpretation because attrition brought on by EFS events may have selected participants with the greatest results. The statistics also point to a quicker return to pretreatment quality of life with axi-cel than with SOC. Treatment options for second-line R/R LBCL should be influenced by axi-better cel's clinical results and patient experience compared to SOC.

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Can behavior be considered sexual harassment if someone doesn't intend to be offensive, but another person takes offense

alexira [117]

Answer: Sexual Harassment of a student interferes with a

student’s right to receive an education free from

discrimination.

Sexual harassment is unwelcome conduct of a sexual

nature.

Sexual Harassment Can Be In the Form of:

Verbal Harassment

Non-Verbal Harassment

Physical Harassment

Explanation: •Federal law Title IX of the Education Amendments

of 1972 prohibits discrimination on the basis of sex,

including sexual harassment in education

programs and activities.

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4 years ago

Mrs. Davenport enrolled in the ABC Medicare Advantage (MA) plan several years ago. Her doctor recently confirmed a diagnosis of

lorasvet [3.4K]

Answer:

Medicare Advantage (MA) plans are privately planned healthcare offered by contracting with Medicare to provide Part A and Part B health benefits to patients. MA part A plan covers hospital insurance and MA Part B plan covers medical insurance. Most of the MA plans also covers prescription drugs and most of the Medicare services are covered. Common MA plans include Health Maintenance organization (HMO) plans, Preferred provider Organization (PPO) plans, private fee-for-service (PFFS) plans, and Special Needs Plan (SNPs).

Explanation:

Mrs. Davenport is already enrolled in a MA plan before she has developed ESRD. Therefore, her plan will continue after getting the ESRD diagnosis and the MA plan chosen by Mrs. Davenporrt cannot charge more than the original Medicare cost for dialysis and coverage of immunosuppressant drugs. Moreover both part A and part B medicare plans have annual budget for out-of-pocket costs thus the increasing healthcare cost of Mrs. Davenport after the ESRD diagnosis can be covered through renewal of annual budgeting. Moreover, if the previous Medicare advantage plan is not functional in the service area, then Mrs. Davenport could enroll in Special Enrollment period and may get another Medicare advantage plan in their area.

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3 years ago

Read 2 more answers

which nursing interventino is the most effective in preventing a seizure in a client with severe preeclampsia

Nonamiya [84]

Magnesium sulfate ….

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2 years ago

Read this patient’s discharge diagnosis, as follows: Patient Name: Ms. Susan Cloud Date of Admission: 6/23/15 Date of Discharge:

marin [14]

The correct breakdown of the medical term endophthalmitis is: (1) end:- inside; (2) opthalm:- eye; and (3) itis:- inflammation.

Endophthalmitis is the inflammation of the fluids of the eyes, i.e. aqueous and vitreous. The inflammation happens due to infection of the bacteria (Staphylococcus species, Streptococcus species, Gram-negative bacteria) or fungi (Candida, Aspergillus).

Inflammation is the type of immune response generated due to invasion of some microorganisms. Various immune cells and blood cells accumulate at the site of inflammation. The symptoms of inflammation are: redness, swelling, itching, pain, etc. All these symptoms are indicative of the body's healing process.

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3 0

1 year ago

The one that best maintains Intestinal health

Zinaida [17]

A fiber-rich diet is best for intestine health, so the option that says fiber is correct. In the intestine, there is a diverse microbiota that performs a lot of cellular activities and facilitates the digestion process.

<h3>What is the intestine?</h3>

The intestine is an organ located below the stomach that is divided into two sections: the small intestine and the large intestine. The small intestine is responsible for complete digestion, while the large intestine is responsible for minute digestion and the for removal of fecal materials (undigested food). Fiber-rich foods, such as beans, should be consumed in order for the intestinal system to function properly.

Hence, fiber is the correct answer because it is beneficial to the intestine.

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The question is incomplete; here is the complete question.

1) the one that best maintains the intestinal health

a)fiber

b)starch

c)vitamins

d)fats

5 0

1 year ago