Single cell transcriptomics provides insights into hypertrophic cardiomyopathy Wehrens et al. (Eva Van Rooij), 2022, Cell Report
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Answer:
- If individual III-1 marries an unaffected, non-carrier female, none of their children will have DMD
Explanation:
From the options, the only correct statements is that <em>If individual III-1 marries an unaffected, non-carrier female, none of their children will have DMD</em>
<u>DMD is an X-linked recessive trait, meaning that a male individual is either affected or unaffected (can never be a carrier). III-1 is unaffected and if he marries an unaffected, non-carrier female, it means that none of their children will have DMD.</u>
All the children of II-4 and II-5 will always come out with DMD because both parents are affected.
Individuals I-1 and II-1 are males. A male can never be a carrier in for X-linked traits. He is either affected or unaffected and as shown by the pedigree, both males are unaffected (unshaded).
