In my view, only the black plague and class inequality.
<u>The Black Death was a disease of the rat flea that spread and devastated Europe in the fourteenth century, but reached England again in the second outbreak in the sixteenth century.
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The world wars happened in the twentieth century, so they are not an answer.
Unemployment and lack of manpower are the opposite of each other, but none have actually reached England. First, because the population of that time was basically rural and lived subsistence. The event of the Industrial Revolution caused a great demand by manpower, that was satisfied by the peasant class, that migrated to the city.
<u>However, class inequality has always been present. This comes from the age of feudalism, but it grew especially during the Industrial Revolution, which produced a capitalist bourgeoisie and a mass that worked in factories for low wages and abusive hours.</u>
Answer and Explanation:
"What do the stage directions given to Eugene indicate?" The stage directions given to Eugene indicate that "He's angry that his game will be delayed." You can tell this because of text details such as "slams the ball" and "angrily". These key details let us know that Eugene is frustrated about his game being delayed.
<em>Hope you found this helpful! Have a wonderful day! </em>
OBJECTIVES: To analyze the occurrence and types of neoplasias that have developed in patients submitted to orthotopic heart transplantation in the Cardiac Transplantation Program of the Paulista School of Medicine, Federal University of São Paulo.
METHODS: The present study presents an observational analysis of 106 patients submitted to orthotopic heart transplantation from November 1986 to September 2002, who survived for more than 30 days after the procedure. The immunosuppressive regimen consisted of triple therapy with cyclosporin A, azathioprine and corticosteroid. Only two patients received, in addition to triple therapy, the addition of orthoclone OKT-3. The mean follow-up period was 61.4 months. (variation from two months to 192 months).
RESULTS: Twenty-three patients (21.3%) developed neoplasias, of which 56.5% had skin neoplasms, 30.1% had solid tumors and 13.4% had post-transplantation lymphoproliferative disease (PTLD). The mean interval between transplantation and the diagnosis of neoplasia was: skin - 54.9 months, solid tumors - 24.8 months and DLPT - 70.3 months.
CONCLUSIONS: The occurrence of malignant neoplasms was relatively common in the analyzed population. Skin cancer prevailed in relation to other neoplasms and solid tumors were more diagnosed than lymphoproliferative diseases in this series of patients.
