The climate? That would fit I suppose.
Answer:
Gene knockout is a technique used to determine the function of a gene that has already been sequenced, which is achieved by analyzing the phenotype of the individual carrying the knockout mutation(s). Moreover, gene sequencing is a technique used to determine the sequence of a given gene, which allows to determine how gene variants (polymorphisms) may be associated with the phenotypes of the target trait.
Explanation:
In genetics, gene knockout is a technique used to trigger mutations in a (already) sequenced gene in order to inactive its function and observe the resulting phenotype for a particular trait. This approach that starts with the inactivation of a given gene and ends with the phenotype is known as reverse-genetics. On the other hand, gene sequencing can be defined as the methodologies/techniques/tools used to determine the nucleotide base pair sequence of a particular gene. The gene knockout technique involves knowing a priori the gene sequence in order to obtain a gene knockout (gene KO). The combination of the information obtained from these techniques can be used to determine how variation (genetic variation) affects the expression of a phenotypic trait.
Answer:
The correct answer is - option C.
Explanation:
CFTR is a short form of cystic fibrosis transmembrane conductance regulator protein which is caused by a recessive mutation in this protein. This mutation results in the accumulation of mucus in secretory organs.
As the disease is a recessive disease, for the mutant phenotype to expressed both copies of the allele required to be recessive.
The mother is negative for the CFTR. Hence, she will not transfer the mutant allele to her child So, the child would have a wild-type phenotype even if the father having two copies of recessive allele.
Thus, the correct answer is - option C.
Parietal cells produce gastric acid (hydrochloric acid) in response to histamine (via H2 receptors), acetylcholine (M3 receptors) and gastrin (gastrin receptors). Parietal cells contain an extensive secretory network (called canaliculi) from which the HCl is secreted by active transport into the stomach.
