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Kamila [148]
2 years ago
12

A nonfunctional CD4 protein on a helper T cell would result in the helper T cell being unable to _______. A. respond to circulat

ing viral antigens B. lyse tumor cells C. stimulate a cytotoxic T cell D. interact with a class II MHC-antigen complex
Biology
1 answer:
Leona [35]2 years ago
7 0

A nonfunctional CD4 protein on a helper T cell would result in the helper T cell being unable to interact with a class II MHC-antigen complex

Importance of Class II MHC-Antigen complex

  • CD4+ T cell-dependent immunological responses need antigen presentation restricted to MHC class II.

Professional antigen-presenting cells (APCs) perform a range of functions that are essential for the generation of an effective and specific immune response.

  • Dendritic cells (DCs) investigate their surroundings and gather foreign antigens, such as those derived from bacteria or viruses, before activating CD4+ and CD8+ T cells to initiate adaptive immune responses against these antigens.
  • The thymus' DCs and epithelial cells express (and also capture) a diverse set of self-proteins that contribute to both central and peripheral tolerance.

Recognizing the processes involved in the creation (and stability) of peptide-MHC class II complexes in APCs provides crucial information about T cellular metabolism including both normal and pathological settings.

Hence, the correct answer is option D

Learn more about APC here,

brainly.com/question/13588471

# SPJ4

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