Acute leukemia cell lines show the greatest enhancement of chemotherapeutic activity.
<h3>What is acute leukemia?</h3>
- It is a malignancy of the blood and bone marrow.
- Without treatment, it advances quickly and mostly affects developing cells, which are unable to perform their usual roles.
- A condition that may be challenging to treat.
- Clinical studies for the treatment of acute leukemia are still studying by researchers.
<h3>Which shows the greatest enhancement of chemotherapeutic activity?</h3>
The control of differentiation in human myelogenous leukemia and, in a larger context, the controls of normal myeloid development can be studied using acute leukemia cell lines as model systems.
Acute leukemia 44 nM (CC95 alone) and 0.6 nM (CC95 Combination) show the highest fold enhancement comparing other cell lines.
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Question: (CC95 alone) = treatment 2 alone
Acute leukemia → 44 nM (CC95 alone), 0.6 nM (CC95 Combination)
Fibrosarcoma → 86 μM (CC95 alone), 6.7 μM (CC95 Combination)
Cervical carcinoma → 53 μM (CC95 alone), 5.2 μM (CC95 Combination)
Noncancerous fibroblast → 15 μM (CC95 alone), 16 μM (CC95 Combination)
Compared to treatment with Compound 2 alone, which cell line shows the greatest enhancement of chemotherapeutic activity as a result of sensitization by Compound 1?
A.Acute leukemia
B.Fibrosarcoma
C.Cervical carcinoma
D.Noncancerous fibroblast
