Specific macrophage populations help by promoting both cardiac scar deposition and subsequent resolution in adult zebrafish. It is a correct statement.
<h3>What is the effect of macrophages on zebrafish?</h3>
There is an inflammatory response to tissue injury. It is an important part of the process of repair. Scar tissue deposition is a direct downstream consequence of this kind of response in several tissues including the heart tissue.
Adult zebrafish do not only have the ability to regenerate lost cardiomyocytes. They can also remodel and resolve a scar which is extracellular, in tissues like the heart. This resolution of the scar is a poorly understood process.
Therefore, specific macrophage populations help by promoting both cardiac scar deposition and subsequent resolution in adult zebrafish.
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