Question

In humans, a brown eyed man whose father was brown eyed and whose mother was blue eyed, married a blue eyed woman whose father and mother were both brown eyed. The couple has a blue eyed son. For which individuals can you be sure of the genotypes? What genotypes are possible for the others? (SHOW WORKING AND PUNNET SQUARE)

Answer 1

Only the father of the brown-eyed man, who also had brown eyes, cannot be positively recognised by genotyping. We can infer that he carried at least one dominant B allele from the fact that he had brown eyes. He was either homozygous dominant BB or heterozygous Bb, although this cannot be determined. These genotypes (BB or Bb) might both exist based on the information provided.

Individual Genotypes: Based on the information given, a geneticist is confident about the genotypes of the following people: The father of the brown-eyed man: The mother of the blue-eyed man with brown eyes is: bb Bb Brown-eyed man (because his mother could have only contributed a b allele to him) bb Blue-eyed woman Father of the blue-eyed woman (had brown eyes): Bb (for woman to have blue eyes, father must have contributed b allele) The mother of the blue-eyed woman had brown eyes. Bb (for woman to have blue eyes, mother must have contributed b allele) Brown-eyed man and blue-eyed woman's blue-eyed son: bb (confirms that brown-eyed man carries b allele).

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