Examining tumor tissue for driver mutations can help plan treatments that stop cancer cells from growing.
tumors was EGFR, followed by TP53 (18%), SETD2 (11%) and SMARCA4 (11%). More than 72% (81/112) of cases have mutations in at least one driver gene.
For example, the TP53 tumor suppressor gene is a driver gene, but it is only functional when both alleles of her TP53 gene are mutated. Furthermore, mutations can act as drivers only at certain stages of cancer.
